Your Address : Globalchemmade--Changchun Sinobiomaterials Co.,Ltd.
Name:Changchun Sinobiomaterials Co.,Ltd.
Type:Others
Tel:+86-0431-89684007
Fax:+86-0431-89684007
Email:mail@sinobiom.com
Address:China(Mainland)
Products buying leads detail
| Product Name: | Poly(DL-lactide-co-glycolide) |  |
| CAS No: | 26780-50-7 | |
| Product Type: | Other Intermediates | |
| Product spec: | 100g/pcs | |
| Packing: | Vacuum packing | |
| Valid Period: | 2030-12-31 | |
| Description: | Name: Poly(DL-lactide-co-glycolide) Product Model: PDLG Chemical Formula : (C6H8O4)m (C4H4O4)n CAS: 26780-50-7 Chemical Structure: Instructions : Poly(DL-lactide-co-glycolide) (PDLGA) is produced from lactic acid and glycolic acid. It is non-toxic and has excellent biodegradability, biocompatibility, film or capsule forming ability. PDLGA is widely used in pharmaceutical, medical engineering materials and modern industrial fields. In the United States, PDLGA has been approved by the FDA and is formally included in the United States pharmacopoeia as pharmaceutical materials. PDLGA is a amorphous polymer. The glass transition temperature (Tg) of PLGA is 40 - 60 °C. It has been widely used in medical surgical sutures, anti-adhesion membrane, tissue engineering scaffolds and so on. The degradation rate of PDLGA increases with the increase of GA proportion. Different types of PDLGA can be produced using differentmonomer ratio . For example, PDLLGA 75:25 indicates that the polymer consists of 75% DL-lactic acid and 25% glycolic acid. The degradation products of PDLGA are lactic acid and glycolic acid, so they do not have toxic side effects when used as the pharmaceutical and biological materials. PDLGA has been widely used in biomedical fields, such as medical anti-adhesion membrane, skin graft, stitched wound, injectable microcapsules, microspheres, implants, scaffolds for tissue engineering. Appearance : White or pale yellow particles DL-lactide/Glycolic（mol/mol）: 85/15、75/25、50/50 IV (Intrinsic viscosity) : 0.2-1.8 dL/g Specific Rotation ( ，chloroform): -10 - +10° Glass Transition Temperature: 48-53°C Melting Point : Amorphous Residual Monomers : <1% Residual Solvents: < 0.05% Extractable Heavy Metals: < 10 ppm Stannum (Catalyst): < 200 ppm Density: 1.24 g/cm3 Sulfate Ash: < 0.05% Model Model Ratio DL-LA/GA IV DL-LA/GA Proportional Range IV Range dL/g PDLG85-03 85/15 0.3 82/18-88/12 0.20-0.40 PDLG85-05 85/15 0.5 82/18-88/12 0.40-0.70 PDLG85-08 85/15 0.8 82/18-88/12 0.70-1.00 PDLG85-12 85/15 1.2 82/18-88/12 1.00-1.40 PDLG85-16 85/15 1.6 82/18-88/12 1.40-1.80 PDLG85-20 85/15 2.0 82/18-88/12 >1.80 PDLG75-03 75/25 0.3 72/28-78/22 0.20-0.40 PDLG75-05 75/25 0.5 72/28-78/22 0.40-0.70 PDLG75-08 75/25 0.8 72/28-78/22 0.70-1.00 PDLG75-12 75/25 1.2 72/28-78/22 1.00-1.40 PDLG75-16 75/25 1.6 72/28-78/22 1.40-1.80 PDLG75-20 75/25 2.0 72/28-78/22 >1.80 PDLG50-03 50/50 0.3 47/53-53/47 0.20-0.40 PDLG50-05 50/50 0.5 47/53-53/47 0.40-0.70 PDLG50-08 50/50 0.8 47/53-53/47 0.70-1.00 PDLG50-12 50/50 1.2 47/53-53/47 1.00-1.40 PDLG50-16 50/50 1.6 47/53-53/47 1.40-1.80 PDLG50-20 50/50 2.0 47/53-53/47 >1.80 | |